Thousands are sharing side effects of weight-loss drugs doctors may miss, study suggests – CTV
April 14, 2026
Researchers who used AI to analyze hundreds of thousands of social media posts say they have identified unreported GLP-1 side effects, including menstrual changes, fatigue and temperature-related symptoms, suggesting these patterns warrant further investigation.
In a new study, published in Nature Health, researchers said the patient-reported side effects to the popular weight loss drugs may not be fully captured in clinical trials or regulatory documents. Still they caution that this study cannot establish cause and effect.
The peer-reviewed research used artificial intelligence to analyze more than 400,000 posts on Reddit from nearly 70,000 users discussing drugs such as semaglutide, which includes brand names like Ozempic and Wegovy, and tirzepatide branded as Mounjaro or Zepbound.
The researchers analyzed this data set of posts spanning from May 2019 through June 2025.
