Ozempic microdosing: Weight-loss hack or just a placebo? – GLOBAL

May 6, 2025

As weight-loss injectables like Ozempic skyrocket in popularity, a new offshoot trend is starting to take hold: microdosing.

Instead of following the standard dosing guidelines, some people are experimenting with smaller amounts of GLP-1 medications like Ozempic, Wegovy and Mounjaro. The reasons vary — from trying to stretch out expensive prescriptions to avoiding the side effects that can come with higher doses.

This off-label approach has picked up traction online. Podcasts, social media posts and YouTube videos feature users sharing personal stories of shedding pounds through lower-than-recommended doses.

But here’s the thing: using smaller doses for weight loss hasn’t been rigorously studied. Because it’s considered off-label, there’s little clinical evidence to show whether this kind of do-it-yourself dosing is actually effective, or just anecdotal.

Read more: https://globalnews.ca/news/11164205/ozempic-microdosing-weight-loss-hack-placebo/

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