Mpox vaccine is 58% effective after one dose, Canadian study finds – GLOBAL

September 11, 2024

A single dose of the mpox vaccine offers moderate protection against the virus, according to a new Canadian study. While “moderate” might not sound impressive, the researchers describe the results as “terrific” and hope more Canadians at risk will continue to get vaccinated.

The study, published Wednesday in the BMJ, found that a single dose of the Modified vaccinia Ankara-Bavarian Nordic (MVA-BN) was 58 per cent effective in protecting against the mpox infection.

No randomized clinical trials have yet been conducted to test the effectiveness of vaccination against mpox. Previous estimates, based on observational studies, suggested that a single dose of the vaccine could be anywhere from 36-per cent to 86-per cent effective, the study said.

“It’s important because prior to the emergency use of this vaccine to try and reduce infections during a global outbreak that also affected Canada, there was no previous clinical trials to tell us how well this vaccine might work in the real world during an outbreak,” said Dr. Sharmistha Mishra, the study’s co-author and associate professor in the Department of Medicine at the University of Toronto.

Read more: https://globalnews.ca/news/10749976/mpox-vaccine-single-dose-effective-canadian-study/

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