Canadian university researchers find ‘most effective’ treatment for excessive daytime sleepiness – CTV

May 11, 2023

Researchers from McMaster University have found what they call the “most effective” treatment for people with obstructive sleep apnea (OSA) who suffer from excessive daytime sleepiness (EDS).

Dena Zeraatkar and Tyler Pitre published their results in the peer-reviewed publication Annals of Internal Medicine, claiming the drug solriamfetol is “likely the best medication” for EDS.

Their findings are based on a systematic review of 14 clinical trials of anti-fatigue medications involving 3,085 people, as well as analysing data from MEDLINE, CENTRAL, EMBASE and in a specific network meta-analysis.

Their research was conducted from October 2022 to January 2023.

EDS is when someone falls asleep or has a desire for sleep while expected to be awake, and it is often a symptom of sleep-related disorders.

The standard treatment for OSA is a positive airway pressure (PAP) mask that uses compressed air to support lung airways during sleep. However, some people with OSA still experience EDS and may benefit from anti-fatigue medication.

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